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Antigenic Specificity | PD-L1/CD274 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA, WB, IHC, IF, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Please decide the specifity by homology. Programmed cell death ligand 1(CD274, or B7-H1, PD-L1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are keyregulators of the adaptive immune response. CD274 is suggested a negative regulator of T and B cell, and play important role in mediating tolerance of lymphocytes to self-antigens. It also involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. PD-L1 is a 290 aa transmembrane protein with a calculated molecular weight of 33 k |
Immunogen | Immunogen: CD274 molecule Calculated MW: 50 kDa, 70 kDa |
Other Names | [B7 H, B7 H1, B7 homolog 1, B7H1, CD274, CD274 molecule, PD L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, PD-L1, PD-L1/CD274,Programmed death ligand 1] |
Gene, Accession # | [PD-L1/CD274], UniProt: Q9NZQ7 |
Catalog # | MBS7602513 |
Price | $265 |
Order / More Info | PD-L1/CD274 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |