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Antigenic Specificity | IRF3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Interferon regulatory factor 3(IRF3) detection. Tested with WB in Human. Background: IRF3(interferon regulatory factor 3) is a member of the interferon regulatory transcription factor(IRF) family. The IRF3 gene is mapped on 19q13.33. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. IRF3 plays an important role in the innate immune system's response to viral infection. Aggregated MAVS have been found to activate IRF3 dimerization. Although IRF3 increased transcriptional activity from an ISRE-containing promoter, expression of IRF3 as a Gal4 fusion protein did not activate expression of a chloramphenicol acetyltransferase(CAT) |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human IRF3 (409-427aa KAYLQDLVEGMDFQGPGES), different from the related mouse and rat sequences by five amino acids. |
Other Names | [Interferon regulatory factor 3; interferon regulatory factor 3; Interferon regulatory factor 3; IRF 3; IRF-3; IRF3; IRF3_HUMAN; MGC94729], [IRF3; IRF3; IRF-3] |
Gene, Accession # | [IRF3], Gene ID: 3661, NCBI: Q14653.1, UniProt: Q14653 |
Catalog # | MBS176072 |
Price | $280 |
Order / More Info | IRF3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |