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Antigenic Specificity | CD14 |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages. |
Immunogen | Immunogen: Purified recombinant fragment of human CD14 expressed in E. Coli. |
Other Names | [CD14], [K8; K8] |
Gene, Accession # | [CD14], Gene ID: 4961462, NCBI: YP_001129403.1 |
Catalog # | MBS850988 |
Price | $280 |
Order / More Info | CD14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |