Human Serine/threonine-protein kinase PAK 2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Serine/threonine-protein kinase PAK 2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionSerine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Phosphorylates JUN and plays an important role in EGF-induced cell proliferation. Phosphorylates many other substrates includi
ImmunogenImmunogen: Recombinant human Serine/threonine-protein kinase PAK 2 protein (1-212aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1519 / sc-7117 / sc-1872
Other Names[Gamma-PAK; PAK65; S6/H4 kinase; p21-activated kinase 2; PAK-2; p27; p34; C-t-PAK2; PAK2], [PAK2; PAK2; PAK65; PAKgamma; PAK-2; p27; p34]
Gene, Accession #[PAK2], Gene ID: 5062, NCBI: NP_002568.2, UniProt: Q13177
Catalog #MBS1497290
Price$120, $160
Order / More InfoHuman Serine/threonine-protein kinase PAK 2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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