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Antigenic Specificity | KMT6/EZH2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: KMT6 / EZH2 Antibody detects endogenous levels of total KMT6 / EZH2. Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates ' Lys-9' and ' Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate ' Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. |
Immunogen | Immunogen: A synthesized peptide derived from human KMT6 / EZH2 |
Other Names | [histone-lysine N-methyltransferase EZH2 isoform c; Histone-lysine N-methyltransferase EZH2; histone-lysine N-methyltransferase EZH2; enhancer of zeste 2 polycomb repressive complex 2 subunit; ENX-1; Enhancer of zeste homolog 2] |
Gene, Accession # | [KMT6/EZH2], Gene ID: 2146, NCBI: NP_001190176.1, UniProt: Q15910 |
Catalog # | MBS4750286 |
Price | $335 |
Order / More Info | KMT6/EZH2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |