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Antigenic Specificity | TMPRSS2 (Center), 314-343 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TMPRSS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the Central region of human TMPRSS2. TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. |
Immunogen | n/a |
Other Names | [Transmembrane protease serine 2; 3421-; Serine protease 10; Transmembrane protease serine 2 non-catalytic chain; Transmembrane protease serine 2 catalytic chain; TMPRSS2; PRSS10] |
Gene, Accession # | [TMPRSS2], Gene ID: 7113, NCBI: NP_001128571.1, UniProt: O15393 |
Catalog # | MBS9201009 |
Price | $165, $370 |
Order / More Info | TMPRSS2 (Center), 314-343 Antibody from MYBIOSOURCE INC. |
Product Specific References | Gopalan,A., Cancer Res. 69 (4), 1400-1406 (2009) Hofer,M.D., Cancer Res. 69 (2), 640-646 (2009) |