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Antigenic Specificity | MAPK2 |
Clone | polyclonal |
Host Species | Chicken |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.5 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Overview: Stress-activated serine/threonine-protein kinase involved in cytokines production, endocytosis, reorganization of the cytoskeleton, cell migration, cell cycle control, chromatin remodeling, DNA damage response and transcriptional regulation. Following stress, it is phosphorylated and activated by MAP kinase p38-alpha/MAPK14, leading to phosphorylation of substrates. Phosphorylates serine in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue. Phosphorylates ALOX5, CDC25B, CDC25C, ELAVL1, HNRNPA0, HSF1, HSP27/HSPB1, KRT18, KRT20, LIMK1, LSP1, PABPC1, PARN, PDE4A, RCSD1, RPS6KA3, TAB3 and TTP/ZFP36.Structure: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Contains 1 |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 300-350 on human Mitogen-activated protein kinase 2. Conjugation: Unconjugated |
Other Names | [Affinity Purified Mitogen-activated protein kinase 2; ERK 2; ERT1; Extracellular Signal Regulated Kinase 2; MAP kinase 2; MAPK 2; Mitogen-activated protein kinase 2; protein kinase, mitogen-activated, 2; protein tyrosine kinase ERK2] |
Gene, Accession # | [MAPK2], Gene ID: 9261, NCBI: NP_116584, UniProt: P49137 |
Catalog # | MBS5400507 |
Price | $390 |
Order / More Info | MAPK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |