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Antigenic Specificity | WSB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: WSB1 antibody detects endogenous levels of WSB1. Function: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation.Subunit Structure: Interacts with DIO2. Component of the probable ECS(WSB1) E3 ubiquitin ligase complex which contains CUL5, RNF7/RBX2, Elongin BC complex and WSB1. Component of a probable ECS-like E3 ubiquitin-protein ligase complex which contains CUL5, RBX1, Elongin BC complex and WSB1. Interacts with CUL5, RNF7, ELOB and ELOC. Bind |
Immunogen | Immunogen: A synthesized peptide derived from human WSB1. Subcellular Location: Intracellular Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Rabbit, Dog Similarity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (100%), Rabbit (100%), Dog (100%) |
Other Names | [SOCS box containing WD protein SWiP 1; SWIP1; WD repeat and SOCS box containing 1; WD repeat and SOCS box containing protein 1; WSB 1] |
Gene, Accession # | [WSB1], Gene ID: 26118, NCBI: NP_056441.6, UniProt: Q9Y6I7 |
Catalog # | MBS9603733 |
Price | $240, $280 |
Order / More Info | WSB1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |