EXOSC6 (N-term), 12-38 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEXOSC6 (N-term), 12-38
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis EXOSC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-38 amino acids from the N-terminal region of human EXOSC6. This gene product constitutes one of the subunits of themultisubunit particle called exosome, which mediates mRNAdegradation. The composition of human exosome is similar to itsyeast counterpart. This protein is homologous to the yeast Mtr3protein. Its exact function is not known, however, it has beenshown using a cell-free RNA decay system that the exosome isrequired for rapid degradation of unstable mRNAs containing AU-richelements (AREs), but not for poly(A) shortening. The exosome doesnot recognize ARE-containing mRNAs on its own, but require
Immunogenn/a
Other Names[Exosome complex component MTR3; Exosome component 6; mRNA transport regulator 3 homolog; hMtr3; p11; EXOSC6; MTR3]
Gene, Accession #[EXOSC6], Gene ID: 118460, NCBI: NP_478126.1, UniProt: Q5RKV6
Catalog #MBS9201834
Price$165, $370
Order / More InfoEXOSC6 (N-term), 12-38 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSeth, D., et al. J. Hepatol. 48(4):614-627(2008) Lehner, B., et al. Genome Res. 14(7):1315-1323(2004) Raijmakers, R., et al. J. Mol. Biol. 323(4):653-663(2002) van Hoof, A., et al. Curr. Biol. 12 (8), R285-R287 (2002) : Raijmakers, R., et al. J. Mol. Biol. 315(4):809-818(2002)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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