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Antigenic Specificity | Mouse CD279/PD-1 |
Clone | monoclonal |
Host Species | Rat |
Reactive Species | mouse |
Isotype | n/a |
Format | PE-Cy7 conjugate |
Size | 20 tests, 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts. |
Immunogen | n/a |
Other Names | [Mouse CD279/PD-1; PD-1; Programmed Death-1] |
Gene, Accession # | [CD279/PD-1], Gene ID: 18566, NCBI: Q02242.1, UniProt: Q02242 |
Catalog # | MBS2558948 |
Price | $85, $90, $115 |
Order / More Info | Mouse CD279/PD-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |