Mouse CD279/PD-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CD279/PD-1
Clonemonoclonal
Host SpeciesRat
Reactive Speciesmouse
Isotypen/a
FormatPE-Cy7 conjugate
Size20 tests, 50 tests, 100 tests
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionCD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
Immunogenn/a
Other Names[Mouse CD279/PD-1; PD-1; Programmed Death-1]
Gene, Accession #[CD279/PD-1], Gene ID: 18566, NCBI: Q02242.1, UniProt: Q02242
Catalog #MBS2558948
Price$85, $90, $115
Order / More InfoMouse CD279/PD-1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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