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Antigenic Specificity | Exonuclease 1/EXO1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS), Direct ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for Exonuclease 1/EXO1 detection. Tested with WB, FCM, Direct ELISA in Human.Background: Exonuclease 1 is an enzyme that in humans is encoded by the EXO1 gene. It is mapped to 1q43. This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. |
Immunogen | Immunogen: E. coli-derived human Exonuclease 1/EXO1 recombinant protein (Position: M1-K294). |
Other Names | [Exodeoxyribonuclease 1; Exodeoxyribonuclease I; EXO I; Exonuclease I; Protein DHS1; EXO1; DHS1; YOR033C; OR26.23] |
Gene, Accession # | [EXO1], Gene ID: 9156, NCBI: NP_003677.4, UniProt: Q9UQ84 |
Catalog # | MBS1752834 |
Price | $280 |
Order / More Info | Exonuclease 1/EXO1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Zakharyevich K, Tang S, Ma Y, Hunter N (2012). Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvase. Cell. 149 (2): 334-47. 2. Wilson DM III, Carney JP, Coleman MA, Adamson AW, Christensen M, Lamerdin JE (September 1998). Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1. Nucleic Acids Res. 26 (16): 3762-8. doi:10.1093/nar/26.16.3762. 3. Schmutte C, Marinescu RC, Sadoff MM, Guerrette S, Overhauser J, Fishel R (November 1998). Human exonuclease I interacts with the mismatch repair protein hMSH2. Cancer Res. 58 (20): 4537-42. |