Exonuclease 1/EXO1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityExonuclease 1/EXO1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Flow Cytometry (FC/FACS), Direct ELISA (EIA)
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DescriptionSpecificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for Exonuclease 1/EXO1 detection. Tested with WB, FCM, Direct ELISA in Human.Background: Exonuclease 1 is an enzyme that in humans is encoded by the EXO1 gene. It is mapped to 1q43. This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.
ImmunogenImmunogen: E. coli-derived human Exonuclease 1/EXO1 recombinant protein (Position: M1-K294).
Other Names[Exodeoxyribonuclease 1; Exodeoxyribonuclease I; EXO I; Exonuclease I; Protein DHS1; EXO1; DHS1; YOR033C; OR26.23]
Gene, Accession #[EXO1], Gene ID: 9156, NCBI: NP_003677.4, UniProt: Q9UQ84
Catalog #MBS1752834
Price$280
Order / More InfoExonuclease 1/EXO1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Zakharyevich K, Tang S, Ma Y, Hunter N (2012). Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvase. Cell. 149 (2): 334-47. 2. Wilson DM III, Carney JP, Coleman MA, Adamson AW, Christensen M, Lamerdin JE (September 1998). Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1. Nucleic Acids Res. 26 (16): 3762-8. doi:10.1093/nar/26.16.3762. 3. Schmutte C, Marinescu RC, Sadoff MM, Guerrette S, Overhauser J, Fishel R (November 1998). Human exonuclease I interacts with the mismatch repair protein hMSH2. Cancer Res. 58 (20): 4537-42.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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