Fractin Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Fractin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | serum |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes the 32kD human Fractin fragment, but not full-length beta actin. Species Crossreactivity: mouse and rat. During apoptosis, beta actin is cleaved by activated caspase 3 between Asp244 and Gly245. This cleavage results in the release of an approximately 130 amino acid (15kD) fragment from the C-terminus of beta actin and a 32kD (244 amino acid) N-terminal fragment of actin, known as Fractin. The C-terminus of the Fractin fragment represents an apoptosis-specific neoepitope that is not antigenic in native full-length beta actin and therefore presents a novel and specific marker for distinguishing apoptotic from necrotic cells. |
| Immunogen | Immunogen: Synthetic peptide corresponding to the last five amino acids, K-YELPD, of the C-terminus of the 32kD human Fractin fragment of beta-Actin. Species Sequence Homology: Mouse, rat, feline, porcine, ovine, bovine, canine, rabbit and guinea pig. |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS614549 |
| Price | $700 |
| Order / More Info | Fractin Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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