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Antigenic Specificity | CADM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total CADM1 protein. Homologous to the poliovirus receptor (PVR/CD155), the Nectin immunoglobulin superfamily comprises four known isoforms, Nectin 1, 2, 3 and 4 (also designated TSLC1). TSLC1 is encoded by a tumor-suppressor gene in human non-small-cell lung cancer mapping to chromosome 11q23.2. The TSLC1 protein is an N-linked membrane glycoprotein that co-localizes with the Actin filament-binding protein, afadin, at cadherin-based adherens junctions in MDCKII epithelial cells. TSLC1 also interacts with the tumor-suppressor gene product DAL-1 (for differentially expressed in adenocarcinoma of the lung protein 1) to target Actin rearragement and cellular motility. TSLC1 may also form homodimers that |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human CADM1. |
Other Names | [BL2; ST17; IGSF4; NECL2; RA175] |
Gene, Accession # | [CADM1], Gene ID: 23705, NCBI: NP_001091987.1, UniProt: Q9BY67 |
Catalog # | MBS9406473 |
Price | $255 |
Order / More Info | CADM1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |