MAD2L2 (C-term) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MAD2L2 (C-term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This MAD2L2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 198-231 amino acids from the C-terminal region of human MAD2L2. Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the |
| Immunogen | n/a |
| Other Names | [Mitotic spindle assembly checkpoint protein MAD2B; Mitotic arrest deficient 2-like protein 2; MAD2-like protein 2; REV7 homolog; hREV7; MAD2L2; MAD2B; REV7] |
| Gene, Accession # | [MAD2L2], Gene ID: 10459, NCBI: NP_001120797.1, UniProt: Q9UI95 |
| Catalog # | MBS9207597 |
| Price | $165, $370 |
| Order / More Info | MAD2L2 (C-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Nelson K.K.,et al.Biochem. J. 343:673-680(1999). Hirota T.,et al.Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases. Cahill D.P.,et al.Genomics 58:181-187(1999). Murakumo Y.,et al.J. Biol. Chem. 275:4391-4397(2000). Ota T.,et al.Nat. Genet. 36:40-45(2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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