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Antigenic Specificity | LAMP-2 (CT) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Autophagy, the process of bulk degradation of cellular proteins thromugh an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components and is negatively regulated by TOR (Target of rapamycin). LAMP-2, a highly glycosylated protein associated with the lysosome, has recently been shown to be important in autophagy as mice deficient in this protein failed to convert autophagic vacuoles into vacuoles leading to impaired degradation of long-lived proteins. This correlates with the finding that human LAMP-2 deficiency causing Danon's disease is ass |
Immunogen | Immunogen: LAMP-2 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human LAMP-2. Positive Control: Western Blot: HepG2 cell lysateImmunocytochemistry: HepG2 cells |
Other Names | [LAMP-2; Lysosome associated membrane protein 2], [LAMP2; LAMP2; LAMPB; CD107b; LAMP-2; LGP110; LAMP-2; Lysosome-associated membrane protein 2] |
Gene, Accession # | [LAMP-2], Gene ID: 3920, NCBI: NP_001116078.1, UniProt: P13473 |
Catalog # | MBS840616 |
Price | $375 |
Order / More Info | LAMP-2 (CT) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |