FLT3 (Ab-591) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFLT3 (Ab-591)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous level of total FLT3 protein. FLT3 encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopo
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.589~593 (Y-F-Y-V-D) derived from Human FLT3.
Other Names[CD135; FLK-2; FLT-3; FLT3; STK-1]
Gene, Accession #[FLT3], Gene ID: 2322, NCBI: NP_004110.2, UniProt: P36888
Catalog #MBS9403311
Price$200, $255
Order / More InfoFLT3 (Ab-591) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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