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Antigenic Specificity | PIG CD144 |
Clone | [123] |
Host Species | Rat |
Reactive Species | n/a |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Immunohistology Frozen, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat anti Pig CD144, clone 123 recognises a 120-130kD a single pass type I membrane protein considered to be the porcine homologue of human CD144, also known as VE-Cadherin or Cadherin-5. VE-cadherin is expressed by endothelial cells and is important in cell-cell adhesion, tight junction integrity and vascular permeabiltiy (Tinsley et al. 1999). VE-Cadherin is highly susceptible to proteolytic degradation. Western blotting and immunofluorescence studies with Rat anti pig CD144, clone 123 demonstrate rearangement and upregulation of VE-cadherin in porcine endothelial cells cultured as part of tissue engineered blood vessels under shear stress conditions rather than static conditions (Lee et al. 2012). |
Immunogen | n/a |
Other Names | [cadherin-5; Cadherin-5; cadherin-5; VE cadherin; VE-cadherin; vascular endothelial cadherin; Vascular endothelial cadherin; VE-cadherin; CD_antigen: CD144], [CDH5; CDH5; VE-cadherin] |
Gene, Accession # | [CD144], Gene ID: 414737, NCBI: NP_001001649.2, UniProt: O02840 |
Catalog # | MBS224684 |
Price | $320 |
Order / More Info | PIG CD144 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |