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Antigenic Specificity | AMACR |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels AMACR(C-terminus) and does not cross-react with related proteins. UniPort Summary Function: Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers. Entrez Summary: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)-and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopath |
Immunogen | Immunogen: Purified recombinant human AMACR(C-terminus) protein fragments expressed in E Coli. Cellular Localization: Peroxisome; Mitochondrion |
Other Names | [RM; RACE; CBAS4; AMACRD], [RM; RACE; CBAS4; AMACRD] |
Gene, Accession # | [AMACR], Gene ID: 23600, NCBI: NP_001161067.1, UniProt: Q9UHK6 |
Catalog # | MBS857796 |
Price | $300 |
Order / More Info | AMACR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |