ADIPOQ Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityADIPOQ
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionAdiponectin, also termed AdipoQ, Acrp30, apM1 and GBP28, is an adipokine expressed exclusively in brown and white adipocytes (1). It is secreted into the blood and exists in three major forms: a low molecular weight trimer, a medium molecular weight hexamer and a high molecular weight multimer (1). Adiponectin levels are decreased in obese and insulin-resistant mice and humans (2), suggesting that this adipokine is critical to maintain insulin sensitivity. Adiponectin stimulates the phosphorylation of AMPKalpha at Thr172 and activates AMPK in skeletal muscle (3). It also stimulates glucose uptake in myocytes (3). The block of AMPK activation by a dominant-negative AMPKalpha2 isoform inhibits the effect of adiponectin on glucose uptake, indi
ImmunogenImmunogen: Recombinant protein of human ADIPOQ Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1]
Gene, Accession #[ADIPOQ], Gene ID: 9370, NCBI: NP_001171271.1, UniProt: Q15848
Catalog #MBS8501303
Price$310
Order / More InfoADIPOQ Antibody from MYBIOSOURCE INC.
Product Specific References1. Kadowaki, T. et al. (2006) J. Clin. Invest. 116, 1784-1792. 2. Hu, E. et al. (1996) J. Biol. Chem. 271, 10697-10703. 3. Yamauchi, T. et al. (2002) Nat. Med. 8, 1288-1295. 4. Waki, H. et al. (2003) J. Biol. Chem. 278, 40352-40363.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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