Edit |   |
---|---|
Antigenic Specificity | VPS54 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB); Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect endogenous levels of VPS54 in human and rat. Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes; this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:18367545). Within the GARP complex; required to tether the complex to the TGN. Not involved in endocytic recycling |
Immunogen | Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human VPS54 |
Other Names | [HCC8; Vacuolar protein sorting-associated protein 54; Hepatocellular carcinoma protein 8; Tumor antigen HOM-HCC-8; Tumor antigen SLP-8p], [VPS54; VPS54; WR; HCC8; SLP-8p; VPS54L; hVps54L; PPP1R164; HCC8] |
Gene, Accession # | [VPS54], Gene ID: 51542, NCBI: NP_001005739.1, UniProt: Q9P1Q0 |
Catalog # | MBS846078 |
Price | $345 |
Order / More Info | VPS54 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |