CD35 / CR1 (Follicular Dendritic Cell Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD35 / CR1 (Follicular Dendritic Cell Marker)
Clone[CR1/802]
Host SpeciesMouse
Reactive Specieshuman, baboon, monkey
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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DescriptionRecognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb does not block CR1 activity. It is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
ImmunogenImmunogen: Recombinant human CR1 protein
Other Names[C3 binding protein, C3b/C4b receptor, C3BR, C4BR, Complement Component (3b/4b) receptor 1 including Knops blood group system, Complement receptor type 1, KN, Knops blood group antigen], [CR1; CR1; KN; C3BR; C4BR; CD35; C3BR]
Gene, Accession #[CR1], Gene ID: 1378, NCBI: NP_000564.2, UniProt: P17927
Catalog #MBS438802
Price$190, $340, $340
Order / More InfoCD35 / CR1 (Follicular Dendritic Cell Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesAhearn, J.M. and Fearon, D.T. 1989. Structure and function of the complement receptors, CR1 (CD35) and CR2 (CD21). Adv. Immunol. 46: 183-219
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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