Cathepsin D Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Cathepsin D antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Cathepsin D |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Cathepsin D(CTSD) detection. Tested with WB, IHC-P in Human. Background: Cathepsin D is a protein that in humans is encoded by the CTSD gene. This proteinase is a member of the peptidase C1 family, having a specificity similar to but narrower than that of pepsin A. It is mapped to 11p15.5. The cDNA encodes a 412-amino acid protein with 20 and 44 amino acids in a pre- and prosegment, respectively. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease and it has been co |
| Immunogen | Immunogen: E Coli-derived human Cathepsin D recombinant protein (Position: M201-L412). Human Cathepsin D shares 84.4% and 84% amino acid (aa) sequence identity with mouse and rat Cathepsin D, respectively. Ig Type: Rabbit IgG |
| Other Names | [Cathepsin D; CatD; CATD_HUMAN; Cathepsin D heavy chain; Cathepsin D light chain; CathepsinD; CD; Ceroid lipofuscinosis neuronal 10; CLN10; CPSD; CTSD; Lysosomal aspartyl peptidase; Lysosomal aspartyl protease; MGC2311; cathepsin D], [CTSD; CTSD; CPSD; CLN10; HEL-S-130P; CPSD] |
| Gene, Accession # | Gene ID: 1509, NCBI: NP_001900.1, UniProt: P07339 |
| Catalog # | MBS177659 |
| Price | $315 |
| Order / More Info | Cathepsin D Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Faust PL, Kornfeld S, Chirgwin JM (Sep 1985). Cloning and sequence analysis of cDNA for human cathepsin D. Proc Natl Acad Sci U S A 82 (15): 4910-4. 2. Wolf M, Clark-Lewis I, Buri C, Langen H, Lis M, Mazzucchelli L (April 2003). Cathepsin D specifically cleaves the chemokines macrophage inflammatory protein-1 alpha, macrophage inflammatory protein-1 beta, and SLC that are expressed in human breast cancer. Am. J. Pathol. 162 (4): 1183-90. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies