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Antigenic Specificity | G Protein, alpha 16, (Ga16) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Reacts with Ga16. Recognizes human Ga16 and mouse Ga15, but not other G proteins. Ga16 is the only heterotrimeric G proteins with a restricted expression pattern in hematopoietic cells. Differentiation of promyelocytic cells leads to decreased expression of Ga16. This G protein is known to couple a large number of G protein-coupled receptors to PLC-B and can lead to production of the secondary messengers diacylglycerol and inositol phosphates. Targeted deletion of Ga15, a mouse orthologue of human Ga16, causes reduced C5a receptor signaling. Ga16 serves as a marker, in addition to CD34, for hematopoietic progenitor cells. |
Immunogen | Immunogen: E. coli-expressed human Ga16 (aa237-373) |
Other Names | [-G Protein, alpha 16, (Ga16)], [GNA15; GNA15; GNA16; GNA16; G alpha-15; G-protein subunit alpha-15; G alpha-16] |
Gene, Accession # | Gene ID: 2769, NCBI: AAC25616.1, UniProt: P30679 |
Catalog # | MBS625035 |
Price | $465 |
Order / More Info | G Protein, alpha 16, (Ga16) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |