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Antigenic Specificity | RUNX2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, human, monkey, Panda |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.53 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified Runt-related transcription factor 2 isoform 4 Antibody. Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 10-50 on human RUNX2 protein. |
Other Names | [Acute myeloid leukemia 3 protein; Alpha subunit 1; AML3; CBF alpha 1; CBFA1; CCD1; Cleidocranial dysplasia 1; Core binding factor runt domain alpha subunit 1; Core binding factor subunit alpha 1; Oncogene AML 3; OSF 2; Osteoblast specific transcription factor 2; PEBP2 alpha A; PEBP2A1; PEBP2A2; Polyomavirus enhancer-binding protein 2 alpha A subunit; Runt domain; Runt related transcription factor 2 SL3 3 enhancer factor 1 alpha A subunit], [LOC703331; RUNX2] |
Gene, Accession # | [RUNX2], Gene ID: 703331, NCBI: XP_001100855.1 |
Catalog # | MBS540312 |
Price | $390 |
Order / More Info | RUNX2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |