RUNX2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRUNX2
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesbovine, human, monkey, Panda
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration0.53 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionAffinity Purified Runt-related transcription factor 2 isoform 4 Antibody. Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 10-50 on human RUNX2 protein.
Other Names[Acute myeloid leukemia 3 protein; Alpha subunit 1; AML3; CBF alpha 1; CBFA1; CCD1; Cleidocranial dysplasia 1; Core binding factor runt domain alpha subunit 1; Core binding factor subunit alpha 1; Oncogene AML 3; OSF 2; Osteoblast specific transcription factor 2; PEBP2 alpha A; PEBP2A1; PEBP2A2; Polyomavirus enhancer-binding protein 2 alpha A subunit; Runt domain; Runt related transcription factor 2 SL3 3 enhancer factor 1 alpha A subunit], [LOC703331; RUNX2]
Gene, Accession #[RUNX2], Gene ID: 703331, NCBI: XP_001100855.1
Catalog #MBS540312
Price$390
Order / More InfoRUNX2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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