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Antigenic Specificity | GRM5/MGLUR5 (C-Terminus) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.04 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Endogenous levels of human mGluR5. It is predicted to react with mouse and rat mGluR5 protein according to sequence homology. Positive Control: Ramos. Group I of the Metabotropic Glutamate Receptors includes GRM1 and GRM5, receptors that have been shown to activate phospholipase C. Alternativesplice variants of GRM5 have been described, but their full-lengthnature has not been determined. Inflammation results in the activationof mGluR1 and mGluR5 in dorsal horn neurons of the spinal cord, leadingto extracellular signal-regulated kinase (ERK) activation, which is required for nociceptive plasticity and enhanced pain. |
Immunogen | Immunogen: KLH-coupled synthetic peptide from C-terminal of human mGluR5 (Swiss Prot: P41594) Conjugation: Unconjugated |
Other Names | [Rabbit to Human GRM5/MGLUR5; GRM5; GPRC1E; MGLUR5; Mglur5b; MGlu5] |
Gene, Accession # | [GRM5/MGLUR5], Gene ID: 2915, NCBI: NP_000833.1, UniProt: P41594 |
Catalog # | MBS2401745 |
Price | $530 |
Order / More Info | GRM5/MGLUR5 (C-Terminus) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |