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Antigenic Specificity | Human OGR1 (N-TERMINAL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse (expected from sequence) |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Paraffin* |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item detects ovarian cancer G protein-coupled receptor 1 (OGR1), a seven pass transmembrane protein initially cloned from an ovarian cancer cell line. OGR1 has a wide expression, and selectively binds both protons and bioactive lipids. . . OGR1 functions as a proton-sensing G protein-coupled receptor stimulating inositol phosphate production and Ca2+ mobilisation. It is also a receptor for sphingophosphorylcholine and related lysolipids, which antagonise the proton-induced actions mediated by OGR1. . . OGR1 is also expressed early during osteoclastogenesis and plays a role in osteoclast differentiation. MBS222838 detects ovarian cancer G protein-coupled receptor 1 (OGR1), a seven pass transmembrane protein initially cloned from an |
Immunogen | Immunogen: Synthetic peptide: N-terminal domain of human OGR1, conjugated to Keyhole Limpet Hemocyanin (KLH). Histology Positive Control Tissue: Testis. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human OGR1 (NT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
Other Names | [ovarian cancer G-protein coupled receptor 1; Ovarian cancer G-protein coupled receptor 1; ovarian cancer G-protein coupled receptor 1; G-protein coupled receptor 68; ovarian cancer G protein-coupled receptor, 1; sphingosylphosphorylcholine receptor; G protein-coupled receptor 68; G-protein coupled receptor 68; GPR12A; Sphingosylphosphorylcholine receptor], [GPR68; GPR68; OGR1; GPR12A; OGR1; OGR-1] |
Gene, Accession # | [OGR1], Gene ID: 8111, NCBI: NP_001171147.1, UniProt: Q15743 |
Catalog # | MBS222838 |
Price | $725 |
Order / More Info | Human OGR1 (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |