Edit |   |
---|---|
Antigenic Specificity | Rora - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Rora. It was validated on Western BlotTarget Description: Rora is an orphan nuclear receptor. It binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. This isomer binds to the consensus sequence 5'-[AT][TA]A[AT][CGT]TAGGTCA-3'. Regulates a number of genes involved in lipid metabolism such as apolipoproteins AI, APOA5, CIII, CYP71 and PPARgamma, in cerebellum and photoreceptor development including PCP2, OPN1SW, OPN1SM AND ARR3, in circadian rhythm with BMAL1, and skeletal muscle development with MYOD1. IT is a possible receptor for cholesterol or one of its derivatives. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Rora |
Other Names | [nuclear receptor ROR-alpha isoform 1; Nuclear receptor ROR-alpha; nuclear receptor ROR-alpha; RAR-related orphan receptor alpha; Nuclear receptor RZR-alpha; Nuclear receptor subfamily 1 group F member 1; RAR-related orphan receptor A; Retinoid-related orphan receptor-alpha] |
Gene, Accession # | [RORA], Gene ID: 19883, NCBI: NP_038674, UniProt: P51448 |
Catalog # | MBS3207847 |
Price | $335 |
Order / More Info | Rora - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |