TAB1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TAB1 |
| Clone | [1B9-D11-B10] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | 2.8mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Entrez Summary: The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activatio |
| Immunogen | Immunogen: Purified recombinant human TAB1 protein expressed in E Coli. Sensitivity: TAB1 Mouse mAb detects endogenous levels of total TAB1 protein. Sequence Similarities: Contains 1 PPM-type phosphatase domain. |
| Other Names | [2310012M03Rik; 3'-Tab1; MAP3K7IP1; MAP3K7IP1; MGC57664; Mitogenactivatedproteinkinasekinasekinase7interactingprotein1; Mitogen-activatedproteinkinasekinasekinase7-interactingprotein1; TAB1; TAB1; TAB1_HUMAN; TAK1bindingprotein1; TAK1-bindingprotein1; TGFbetaactivatedkinase1bindingprotein1; TGF-betaactivatedkinase1/MAP3K7bindingprotein1; TGF-beta-activatedkinase1andMAP3K7-bindingprotein1; TGF-beta-activatedkinase1-bindingprotein1; Transforminggrowthfactorbetaactivatedkinasebindingprotein1], [TAB1; 3'-Tab1; MAP3K7IP1.] |
| Gene, Accession # | [TAB1], Gene ID: 10454, NCBI: NP_006107.1, UniProt: Q15750 |
| Catalog # | MBS475583 |
| Price | $335 |
| Order / More Info | TAB1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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