Human/Mouse/Rat Foxp3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human/Mouse/Rat Foxp3 |
| Clone | [150D] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG1, kappa |
| Format | fluorescein (FITC) conjugate |
| Size | 20 tests, 50 tests, 100 tests |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | FOXP3 is a 50-55 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4+/CD25- cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in scurfy mice. Overexpression of FOXP3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity. In human, unlike in mouse, two isoforms of FOXP3 have been reported: one |
| Immunogen | n/a |
| Other Names | [Human/Mouse/Rat Foxp3; Forkhead box protein P3; IPEX; JM2; Foxp3] |
| Gene, Accession # | [Foxp3], Gene ID: 50943, NCBI: NP_001107849.1, UniProt: Q9BZS1 |
| Catalog # | MBS2559502 |
| Price | $100, $125, $165 |
| Order / More Info | Human/Mouse/Rat Foxp3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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