SEMA4C Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySEMA4C
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: SEMA4C antibody detects endogenous levels of total SEMA4C. Function: Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.Subunit Structure: Interacts (via the PDZ-binding motif) with GIPC (via the PDZ domain) (By similarity). Interacts with NCDN (By similarity). Interacts (via the PDZ-binding motif) with DLG4. Interacts with PLXNB2 (By similarity).Similarity: Belongs to t
ImmunogenImmunogen: A synthesized peptide derived from human SEMA4C Subcellular Location: Cell Junction > Synapse > Postsynaptic Cell Membrane > Postsynaptic Density. Cytoplasmic Vesicle > Secretory Vesicle > Synaptic Vesicle Membrane. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit Similarity: Pig (90%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%)
Other Names[KIAA1739; M-SEMA-F; S4c; SEM4C_HUMAN; Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C; SEMA4C; SEMACL1; SEMAF; SEMAI; Semaphorin-4C; UNQ5855/PRO34487]
Gene, Accession #[SEMA4C], Gene ID: 54910, NCBI: NP_060259.4, UniProt: Q9C0C4
Catalog #MBS9608929
Price$240, $280
Order / More InfoSEMA4C Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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