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Antigenic Specificity | SEMA4C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SEMA4C antibody detects endogenous levels of total SEMA4C. Function: Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.Subunit Structure: Interacts (via the PDZ-binding motif) with GIPC (via the PDZ domain) (By similarity). Interacts with NCDN (By similarity). Interacts (via the PDZ-binding motif) with DLG4. Interacts with PLXNB2 (By similarity).Similarity: Belongs to t |
Immunogen | Immunogen: A synthesized peptide derived from human SEMA4C Subcellular Location: Cell Junction > Synapse > Postsynaptic Cell Membrane > Postsynaptic Density. Cytoplasmic Vesicle > Secretory Vesicle > Synaptic Vesicle Membrane. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit Similarity: Pig (90%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%) |
Other Names | [KIAA1739; M-SEMA-F; S4c; SEM4C_HUMAN; Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C; SEMA4C; SEMACL1; SEMAF; SEMAI; Semaphorin-4C; UNQ5855/PRO34487] |
Gene, Accession # | [SEMA4C], Gene ID: 54910, NCBI: NP_060259.4, UniProt: Q9C0C4 |
Catalog # | MBS9608929 |
Price | $240, $280 |
Order / More Info | SEMA4C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |