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Antigenic Specificity | NURR1 (NR4A2) (N-term), 13-42 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: bovine, rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This NURR1 (NR4A2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human NURR1 (NR4A2). Parkinson's disease (PD) is a multifactorial disease that appears to arise from the effects of both genetic and environmental influences. The known genetic factors include multiple genes that have been identified in related parkinsonian syndromes, as well as alpha-synuclein. Genes associated with either PD or Parkinson-related disorders include parkin, DJ-1, ubiquitin C-terminal hydrolase isozyme L1 (UCH-L1), nuclear receptor-related factor 1 (NURR1), and alpha-synuclein. Nurr1 is a transcription factor that is expressed in the embryonic ventral midbrain and is c |
Immunogen | n/a |
Other Names | [Nuclear receptor subfamily 4 group A member 2; Immediate-early response protein NOT; Orphan nuclear receptor NURR1; Transcriptionally-inducible nuclear receptor; NR4A2; NOT; NURR1; TINUR] |
Gene, Accession # | [NR4A2], Gene ID: 4929, NCBI: NP_006177.1, UniProt: P43354 |
Catalog # | MBS9206224 |
Price | $165, $370 |
Order / More Info | NURR1 (NR4A2) (N-term), 13-42 Antibody from MYBIOSOURCE INC. |
Product Specific References | Perlmann T, et al. Cell Tissue Res. 318(1):45-52 (2004) Hsu HC,et al. Curr Drug Targets Inflamm Allergy. 3(4):413-23 (2004) Wallen-Mackenzie A, et al. Genes Dev. 17(24):3036-47 (2003) Ichinose,H., et al. Gene 230 (2), 233-239 (1999) Okabe,T., et al. J. Immunol. 154 (8), 3871-3879 (1995) Mages,H.W., et al. Mol. Endocrinol. 8 (11), 1583-1591 (1994) |