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Antigenic Specificity | CD44v4/5 (Marker of Tumor Metastasis) |
Clone | [3D2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes an epitope encoded by exon v9 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA.The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies. |
Immunogen | Immunogen: Recombinant human full-length CD44v3-10 protein |
Other Names | [LHR; BA-1; chondroitin sulfate proteoglycan 8 (CSPG8); Epican; Extracellular Matrix Receptor III (ECM III); GP90 Lymphocyte Homing Adhesion Receptor; HCAM; HCELL; hematopoietic cell E- and L-selectin ligand; Heparan Sulfate Proteoglycan; Hermes Antigen; HAS; HUTCH I; Hyaluronate Receptor; Indian blood group; Inlu Related p80 Glycoprotein; Ly 24; MDU2; MDU3; MIC4; MUTCH I; Phagocytic Glycoprotein 1 (PGP-1)] |
Gene, Accession # | [CD44], Gene ID: 960, NCBI: NP_000601.3, UniProt: P16070 |
Catalog # | MBS4381433 |
Price | $190, $340, $340 |
Order / More Info | CD44v4/5 (Marker of Tumor Metastasis) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. H. Imam, B. Eriksson K. Oberg. Annals of Oncology 11: 295-300, 2000. 2. Thanakit V, et al. J Med Assoc Thai. 2005 Sep;88 Suppl 4:S30-5. |