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Antigenic Specificity | CDKN1A |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a |
Immunogen | Immunogen: Recombinant protein of human CDKN1A Immunogen Species: Human |
Other Names | [CAP20; CDKN1; CIP1; MDA-6; P21; p21CIP1; SDI1; WAF1] |
Gene, Accession # | [CDKN1A], Gene ID: 1026, NCBI: NP_000380.1, UniProt: P38936 |
Catalog # | MBS9132898 |
Price | $275, $430, $655 |
Order / More Info | CDKN1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |