Human APH1A / APH-1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human APH1A / APH-1 |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | Gibbon, bovine, dog, gorilla, hamster, horse, human, monkey, mouse, porcine, rabbit, rat. predicted reactivity: Bat (at least 90% immunogen sequence identity) |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.05 mg |
| Concentration | 0.5 mg/ml |
| Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human APH1A. This antibody is expected to recognize isoform 1 (NP_001071096.1) and isoform 2 (NP_057106.2). APH1 is a multipass transmembrane protein that interacts with presenilin (see PSEN1; MIM 104311) and nicastrin (APH2; MIM 605254) as a functional component of the gamma-secretase complex. The gamma-secretase complex is required for the intramembrane proteolysis of a number of membrane proteins, including the amyloid-beta precursor protein (APP; MIM 104760) and Notch (MIM 190198). |
| Immunogen | Immunogen Description: Synthetic peptide C-HVTDRSDARLQYG from an internal region of human APH1A (NP_001071096.1; NP_057106.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Dog, Bovine, Horse, Rabbit, Pig (100%). |
| Other Names | [APH1A / APH-1 (Internal) IHC-plus; APH1A; Aph-1alpha; APH-1; CGI-78; PSF; APH-1A; Gamma-secretase subunit APH-1A; Human APH1A; APH-1], [APH-1] |
| Gene, Accession # | [APH1A], Gene ID: 51107, NCBI: NP_057106.2, UniProt: Q96BI3 |
| Catalog # | MBS243196 |
| Price | $530 |
| Order / More Info | Human APH1A / APH-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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