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Antigenic Specificity | BEX1/2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human; mouse; rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: BEX1/2 Antibody detects endogenous levels of BEX1/2. Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity.Similarity: Belongs to the BEX family. |
Immunogen | Immunogen: A synthesized peptide derived from human BEX1/2. Fragment: Fab fragment Predicted Cross Reactivity: : Bovine (80%) |
Other Names | [BEX1/2 - N-terminal] |
Gene, Accession # | [BEX1/2], Gene ID: 84707, UniProt: Q9BXY8 |
Catalog # | MBS9611604 |
Price | $240, $280 |
Order / More Info | BEX1/2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |