HLA-DObeta Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | HLA-DObeta |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.03 mL, 0.1 mL, 0.2 mL |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: HLA-DObeta Polyclonal Antibody detects endogenous levels of HLA-DObeta protein. HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. |
| Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human HLA-DObeta at AA range: 10-90 |
| Other Names | [Rabbit HLA-DObeta; HLA-DOB; HLA class II histocompatibility antigen; DO beta chain; MHC class II antigen DOB] |
| Gene, Accession # | [HLA-DObeta], Gene ID: 3112, NCBI: NP_002111.1, UniProt: P13765 |
| Catalog # | MBS9702239 |
| Price | $130, $220, $325 |
| Order / More Info | HLA-DObeta Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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