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Antigenic Specificity | CYP8B1 (C-term), 471-501 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Flow Cytometry (FC/FACS), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CYP8B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 471-501 amino acids from the C-terminal region of human CYP8B1. CYP8B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. Th |
Immunogen | n/a |
Other Names | [7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase; 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase; CYPVIIIB1; Cytochrome P450 8B1; Sterol 12-alpha-hydroxylase; CYP8B1; CYP12] |
Gene, Accession # | [CYP8B1], Gene ID: 1582, NCBI: NP_004382.2, UniProt: Q9UNU6 |
Catalog # | MBS9202980 |
Price | $165, $370 |
Order / More Info | CYP8B1 (C-term), 471-501 Antibody from MYBIOSOURCE INC. |
Product Specific References | Zhang,M. et.al., J. Biol. Chem. 276 (45), 41690-41699 (2001) Wang,J., et.al., Histochem. Cell Biol. 123 (4-5), 441-446 (2005) |