CUL2 (N-term), 150-179 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CUL2 (N-term), 150-179 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.45 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CUL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-179 amino acids from the N-terminal region of human CUL2. Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the ECS |
| Immunogen | n/a |
| Other Names | [Cullin-2; CUL-2; CUL2] |
| Gene, Accession # | [CUL2], Gene ID: 8453, NCBI: NP_001185706.1, UniProt: Q13617 |
| Catalog # | MBS9205714 |
| Price | $165, $370 |
| Order / More Info | CUL2 (N-term), 150-179 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Park, S.W., et al. APMIS 117(12):880-885(2009) Argyropoulos, G., et al. Physiol. Genomics 36(2):79-88(2009) Barrett, J.C., et al. Nat. Genet. 40(8):955-962(2008) Maeda, Y., et al. J. Biol. Chem. 283(23):16084-16092(2008) Huh, K., et al. J. Virol. 81(18):9737-9747(2007) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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