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Antigenic Specificity | ZEB2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ZEB2 antibody is predicted to not cross-react with ZEB1. ZEB2 Antibody: ZEB2, initially identified as Smad interacting-protein 1, is normally located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Like the homologous ZEB1, ZEB2 inhibits the transcription of the E-cadherin gene and induces epithelial-mesenchymal transition, a genetic program controlling cell migration during embryonic development and wound healing, in vitro. ZEB2 can also protect cells from DNA damage-induced apoptosis, suggesting that its expression may contribute to tumor progression. Recent evidence has shown that ZEB2 is often observed in the cytoplasm in numerous cancer tissues, indicating that i |
Immunogen | Immunogen: ZEB2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human ZEB2. Buffer: ZEB2 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [ZEB2; SIP1; SIP-1; ZFHX1B; HSPC082; SMADIP1; KIAA0569; SIP1; ZFX1B; HRIHFB2411; Zinc finger E-box-binding homeobox 2; Smad-interacting protein 1; zinc finger E-box binding homeobox 2], [ZEB2; ZEB2; SIP1; SIP-1; ZFHX1B; HSPC082; SMADIP1; KIAA0569; SIP1; ZFHX1B; ZFX1B; SMADIP1] |
Gene, Accession # | [ZEB2], Gene ID: 9839, NCBI: AAI27103, UniProt: O60315 |
Catalog # | MBS150898 |
Price | $375 |
Order / More Info | ZEB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |