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Antigenic Specificity | HSP40 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | P. Falciparum |
Isotype | n/a |
Format | APC-Cy7 conjugate |
Size | 0.1 mg |
Concentration | 1.8 mg/ml |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~ 62 kDa. Specific to P. Falciparum and does not cross-react to any protein from Human erythrocytes. DnaJ/HSP40 proteins have been preserved throughout evolution and are important for protein translation, folding, unfolding, translocation, and degradation, primarily by stimulating the ATPase activity of chaperone proteins, HSP70s. Because the ATP hydrolysis is essential for the activity of HSP70s, DnaJ/HSP40 proteins actually determine the activity of HSP70s by stabilizing their interaction with substrate proteins. DnaJ/HSP40 proteins all contain the J domain through which they bind to HSP70s. HSP40, also known as HDJ1 (1), is a basic mammalian 40kDa heat shock protein which is not only homologous to the bacterial heat shock protein |
Immunogen | Immunogen: C-terminal peptide of Pf11 0513 conjugated to KLH |
Other Names | [Rabbit P. Falciparum HSP40; DNAJ1; NDAJB1; HDJ1; HSP40; HSPF1; DnaJ homolog subfamily B member 1; Dna J protein homolog 1; Heat shock 40 kDa protein 1; HSP40; heat shock protein 40; Human DnaJ protein 1; hDj-1] |
Gene, Accession # | [HSP40], Gene ID: 811046, NCBI: XP_001348169.3, UniProt: Q8IHM7 |
Catalog # | MBS8004337 |
Price | $510 |
Order / More Info | HSP40 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Ohtsuka K. (1993) Biochem. Biophys. Res. Commun. 197: 235-240. 2. Melville M.W., et al. (1997) PNAS USA. 94: 97-102. 3. Hattori H., Let al. (1992) Cell Structure and Function. 17: 77-86. 4. Ohtsuka K. Masuda A., Nakai A., and Nagata K. (1990) Biochem. Biophys. Res. Commun. 166: 642-647. 5. Bardwell J.C.A., et al. (1986) J. Biol. Chem. 261: 1782-1785. 6. Ohku M., Tamura F., Nishimura S., and Uchida H. (1986) J. Biol. Chem. 261: 1778-1781. |