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Antigenic Specificity | CD72 (B Cell Marker) |
Clone | [BU40] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD5 has been identified as a transmembrane glycoprotein that is expressed on 70% of normal peripheral blood lymphocytes and on virtually all T lymphocytes in thymus and peripheral blood. Activation of T cells through the T cell receptor (TCR) results in tyrosine phosphorylation of CD5, and the absence of CD5 renders T cells hyper-responsive to TCR-mediated activation. CD5 associates with the TCR/CD3 chain, and with the Src family kinase, Lck p56. The C-type lectin superfamily member CD72 is a cell surface negative regulator of B cell activation from the pro-B through the mature B cell stage. CD72 serves as a receptor for CD5. The ability of lymphocytes to respond to antigenic or mitogenic stimulation utilizes both positive and |
Immunogen | Immunogen: HF B1 plasmacytoid cell line. |
Other Names | [B cell differentiation antigen CD72; CD72b; CD72c; Ly-19; Ly-32; Ly-m19; LYB2; Lymphocyte antigen 32] |
Gene, Accession # | [CD72], Gene ID: 971, NCBI: NP_001773.1, UniProt: P21854 |
Catalog # | MBS4381445 |
Price | $190, $340, $340 |
Order / More Info | CD72 (B Cell Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Yoshida, Y., et al. 2015. Arthritis Rheumatol. 67: 1481-1490. |