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Antigenic Specificity | CD68/Sr D1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. |
Immunogen | Immunogen: A synthesized peptide derived from human CD68. Subcellular Localization: Isoform Short: Cell membrane; Single-pass type I membrane protein. Tissue Specificity: Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. |
Other Names | [Macrosialin; Gp110; CD68; CD68], [CD68; CD68; GP110; LAMP4; SCARD1] |
Gene, Accession # | [CD68], Gene ID: 968, NCBI: NP_001035148.1, UniProt: P34810 |
Catalog # | MBS179385 |
Price | $160, $340, $340 |
Order / More Info | CD68/Sr D1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |