IL-33 [12H6D12] Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIL-33 [12H6D12]
Clone[12H6D12]
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1
Formatimmunoaffinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionIL-33 Monoclonal Antibody: Interleukin-33 (IL-33) is a recently identified member of the IL-1 family of cytokines whose other members include IL-1αβ, IL-1Ra and IL-18. Its receptor has been shown to be ST2, an IL-1 receptor family member that also acts as a negative regulator of TLR-IL-1R signaling and IL-1R accessory protein (IL-1RAcP). Receptor binding of IL-33 activates NF-κB and MAP kinases and induces the expression of TH2-associated cytokines such as IL-4, IL-5 and IL-6. Prolonged IL-33 treatment of mice led to the development of eosinophilia, splenomegaly, and severe pathological changes in mucosal organs such as lungs, esophagus and small intestine. Recent experiments have shown that IL-33 can also co-localize with he
ImmunogenImmunogen: Mouse monoclonal IL-33 antibody was raised against the recombinant IL-33 protein. Buffer: IL-33 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[IL-33 [12H6D12] : DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; interleukin 33], [IL33; IL33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; C9orf26; IL1F11; NFHEV; IL-33; IL-1F11; NF-HEV]
Gene, Accession #[IL33], Gene ID: 90865, NCBI: NP_254274, UniProt: O95760
Catalog #MBS150019
Price$375
Order / More InfoIL-33 [12H6D12] Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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