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Antigenic Specificity | IL-33 [12H6D12] |
Clone | [12H6D12] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-33 Monoclonal Antibody: Interleukin-33 (IL-33) is a recently identified member of the IL-1 family of cytokines whose other members include IL-1αβ, IL-1Ra and IL-18. Its receptor has been shown to be ST2, an IL-1 receptor family member that also acts as a negative regulator of TLR-IL-1R signaling and IL-1R accessory protein (IL-1RAcP). Receptor binding of IL-33 activates NF-κB and MAP kinases and induces the expression of TH2-associated cytokines such as IL-4, IL-5 and IL-6. Prolonged IL-33 treatment of mice led to the development of eosinophilia, splenomegaly, and severe pathological changes in mucosal organs such as lungs, esophagus and small intestine. Recent experiments have shown that IL-33 can also co-localize with he |
Immunogen | Immunogen: Mouse monoclonal IL-33 antibody was raised against the recombinant IL-33 protein. Buffer: IL-33 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [IL-33 [12H6D12] : DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; interleukin 33], [IL33; IL33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; C9orf26; IL1F11; NFHEV; IL-33; IL-1F11; NF-HEV] |
Gene, Accession # | [IL33], Gene ID: 90865, NCBI: NP_254274, UniProt: O95760 |
Catalog # | MBS150019 |
Price | $375 |
Order / More Info | IL-33 [12H6D12] Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |