KSHV ORF45 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKSHV ORF45
Clone[2D4A5]
Host SpeciesMouse
Reactive SpeciesKSHV
IsotypeIgG1
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionEntrez Summary: Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma- (2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. ORF45 protein encoded by an immediate-early gene in the KSHV genome is characterized as a phosphorylated protein, and it is localized in the cytoplasm of infected cells. Studies have shown that ORF45 Protein interacted with cellular IRF-7 and blocked virus-mediated phosphorylation and nuclear translocation of IRF-7. In consequence, ORF45 efficiently inhibited virus-induced production of type I IFN. Zhu et al (2003) reported that the
ImmunogenImmunogen: Purified recombinant fragment of KSHV ORF45 expressed in E Coli.
Other Names[ORF45], [ORF45]
Gene, Accession #[KSHV ORF45], Gene ID: 4961474
Catalog #MBS475650
Price$335
Order / More InfoKSHV ORF45 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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