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Antigenic Specificity | Mouse CD54/ICAM-1 |
Clone | [YN1/1.7.4] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b kappa |
Format | unconjugated |
Size | 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry; Immunohistochemistry (Frozen Sections); Immunoprecipitation; Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Mouse CD54/ICAM-1, Mr 95 kDa. CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN- gamma, IL-1, TNF- alpha, lipopolysaccharide and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS673410 |
Price | $230 |
Order / More Info | Mouse CD54/ICAM-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Takei, F. 1985. J. Immunol. 134:1403.2. Horley, K.J., C. Carpenito, B. Baker, F. Takei. 1989. EMBO. J. 8:2889.3. Welder, Clayton A., D.H.S. Lee, F. Takei. 1993. J. Immunol. 150:2203.4. Qin, Lan, et. al. 1996. J. Immunol. 157:5016. |