RAIDD Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRAIDD
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentration0.2 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionBackground: Caspase family of cysteine proteases plays a key role in apoptosis. Caspase-9 is one of the most important caspases among the caspase family members. Upon induction of apoptosis, cytochrome c released from mitochondria associates with procaspase-9/Apaf-1. The complex processes procaspase-9 into a large subunit (35 kDa or 17-25 kDa) and small (10 kDa) by self-cleavage at D315. Activated caspase-9 further cleaves other caspase members including caspase-3, one of the proteases responsible for the proteolytic cleavage of many key proteins in apoptosis. In addition to self-cleavage, procaspase-9 can also be cleaved in vivo by caspase-3 at D330. The process served as a positive feedback to amplify the apoptotic signal in caspase activ
ImmunogenImmunogen: Synthetic peptide surrounding amino acid 171 of human RAIDD
Other Names[CRADD; MGC9163,], [CRADD; CRADD; MRT34; RAIDD; RAIDD]
Gene, Accession #[RAIDD], Gene ID: 8738, NCBI: AAH37905
Catalog #MBS841205
Price$150, $290
Order / More InfoRAIDD Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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