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Antigenic Specificity | MRE11 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Double-strand break repair protein MRE11A is a protein that in humans is encoded by the MRE11A gene. This gene encodes a nuclear protein involved in homologous Recombinantion, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3 |
Immunogen | Immunogen: E Coli-derived human MRE11 recombinant protein (Position: S2-D239). Subcellular Localization: Nucleus. |
Other Names | [Double-strand break repair protein MRE11; Double-strand break repair protein MRE11A; Meiotic Recombinantion 11 homolog 1; MRE11 homolog 1; Meiotic Recombinantion 11 homolog A; MRE11 homolog A; MRE11] |
Gene, Accession # | [MRE11], Gene ID: 4361, NCBI: NP_005581.2, UniProt: P49959 |
Catalog # | MBS1750471 |
Price | $315 |
Order / More Info | MRE11 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |