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Antigenic Specificity | PAK4 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PAK4 |
Other Names | [serine/threonine-protein kinase PAK 4 isoform 1; Serine/threonine-protein kinase PAK 4; serine/threonine-protein kinase PAK 4; p21 (RAC1) activated kinase 4; p21-activated kinase 4] |
Gene, Accession # | [PAK4], Gene ID: 10298, NCBI: NP_001014831.1, UniProt: O96013 |
Catalog # | MBS3221597 |
Price | $335 |
Order / More Info | PAK4 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |