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Antigenic Specificity | SHP2 (Y546), 526-551 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: chicken, mouse, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SHP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 526-551 amino acids from human SHP2. SHP2, also known as PTPN11, is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activ |
Immunogen | n/a |
Other Names | [Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3; PTPN11; PTP2C; SHPTP2] |
Gene, Accession # | [PTPN11], Gene ID: 5781, NCBI: NP_002825.3, UniProt: Q06124 |
Catalog # | MBS9209068 |
Price | $165, $370 |
Order / More Info | SHP2 (Y546), 526-551 Antibody from MYBIOSOURCE INC. |
Product Specific References | Chan, R.J., et al., Blood 105(9):3737-3742 (2005). Sturla, L.M., et al., J. Biol. Chem. 280(15):14597-14604 (2005). Loh, M.L., et al., Leuk. Res. 29(4):459-462 (2005). Wang, Q., et al., J. Biol. Chem. 280(9):8397-8406 (2005). Niihori, T., et al., J. Hum. Genet. 50(4):192-202 (2005). |