SHP2 (Y546), 526-551 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySHP2 (Y546), 526-551
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: chicken, mouse, rat)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
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DescriptionThis SHP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 526-551 amino acids from human SHP2. SHP2, also known as PTPN11, is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activ
Immunogenn/a
Other Names[Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3; PTPN11; PTP2C; SHPTP2]
Gene, Accession #[PTPN11], Gene ID: 5781, NCBI: NP_002825.3, UniProt: Q06124
Catalog #MBS9209068
Price$165, $370
Order / More InfoSHP2 (Y546), 526-551 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesChan, R.J., et al., Blood 105(9):3737-3742 (2005). Sturla, L.M., et al., J. Biol. Chem. 280(15):14597-14604 (2005). Loh, M.L., et al., Leuk. Res. 29(4):459-462 (2005). Wang, Q., et al., J. Biol. Chem. 280(9):8397-8406 (2005). Niihori, T., et al., J. Hum. Genet. 50(4):192-202 (2005).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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