Edit |   |
---|---|
Antigenic Specificity | Human CD55 |
Clone | [4AMEM188] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG2a |
Format | unconjugated |
Size | 500 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | 4AMEM188 reacts with CD56, a 175-220 kDa Neural Cell Adhesion Molecule (NCAM), expressed on 10-25% of peripheral blood lymphocytes, including all CD16+ NK cells and approximately 5% of CD3+ lymphocytes, referred to as NKT cells. It also is present at brain and neuromuscular junctions, certain LGL leukemias, small cell lung carcinomas, neuronally derived tumors, myeloma and myeloid leukemias. CD56 (NCAM) is involved in neuronal homotypic cell adhesion which is implicated in neural development, and in cell differentiation during embryogenesis. |
Immunogen | n/a |
Other Names | [CD55, partial; complement decay-accelerating factor; CD55 molecule (Cromer blood group)] |
Gene, Accession # | [CD55], Gene ID: 1604 |
Catalog # | MBS8537635 |
Price | $350 |
Order / More Info | Human CD55 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Knapp, W et al., eds. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York. 2. Lanier LL. et al. (1991) J. Immunol. 146:4421-4426. 3. Campbell, JJ et al. (2001) J. Immunol. 166:6477-6482. 4. Cooper MD et al. (2001) Trends in Immunol. 22:633-640. 5. Galandrini R et al. (2002) Blood. 100:4581-4589. |